Quadrivalent human papillomavirus recombinant vaccine: The first vaccine for cervical cancers

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Quadrivalent human papillomavirus vaccine.

The lifetime risk of human papillomavirus (HPV) infection exceeds 50%. HPV infection causes >550,000 cases of cervical and anogenital cancer worldwide annually. Infection also causes precancerous lesions and genital warts. HPV types 16 and 18 cause approximately 70% of HPV-related cancers, and HPV types 6 and 11 cause approximately 90% of cases of genital warts. A quadrivalent vaccine for HPV t...

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Postlicensure safety surveillance for quadrivalent human papillomavirus recombinant vaccine.

CONTEXT In June 2006, the Food and Drug Administration licensed the quadrivalent human papillomavirus (types 6, 11, 16, and 18) recombinant vaccine (qHPV) in the United States for use in females aged 9 to 26 years; the Advisory Committee on Immunization Practices then recommended qHPV for routine vaccination of girls aged 11 to 12 years. OBJECTIVE To summarize reports to the Vaccine Adverse E...

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Adverse events and quadrivalent human papillomavirus recombinant vaccine.

Supplementary material http://jama.ama-assn.org/cgi/content/full/302/7/750/DC1 Report Video JAMA Correction Contact me if this article is corrected. Citations Contact me when this article is cited. This article has been cited 6 times. Topic collections Contact me when new articles are published in these topic areas. Medical Error; Drug Therapy; Adverse Effects; Infectious Diseases Viral Infecti...

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Prevention of cervical, vaginal, and vulval cancers: role of the quadrivalent human papillomavirus (6, 11, 16, 18) recombinant vaccine

The relationship between the human papillomavirus (HPV) and malignancies of the uterine cervix, vagina, and vulva has been established. The development of a quadrivalent HPV recombinant prophylactic vaccine represents the first time in history that primary prevention of these cancers is offered to girls and women. The prevalence of oncogenic HPV subtypes in cervical cancers has been the most st...

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A novel vaccine for cervical cancer: quadrivalent human papillomavirus (types 6, 11, 16 and 18) recombinant vaccine (Gardasil®)

Human papillomaviruses (HPVs) are one of the most common sexually transmitted infections and remains a public health problem worldwide. There is strong evidence that HPV causes cervical, vulva and vaginal cancers, genital warts and recurrent respiratory papillomatosis. The current treatments for HPV-induced infections are ineffective and recurrence is common-place. Therefore, to reduce the burd...

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ژورنال

عنوان ژورنال: Journal of Cancer Research and Therapeutics

سال: 2007

ISSN: 0973-1482

DOI: 10.4103/0973-1482.34686